Clinical-stage med-device company with a novel
"Endo-Metabolic" device platform for less-invasively treating obesity
We aim to address obese patients’ unmet demand for a less-invasive yet highly effective obesity treatment
Pioneering Endo-Metabolic Devices for Obesity
Using the body’s Natural Physiology to amplify Satiety
EndoSphere has developed a new category of less-invasive endoscopic medical devices for treating obesity using the body’s natural physiology by focusing on the Duodenum, the upper intestinal organ which functions the body’s “metabolic control center”. We call this new category “Endo-Metabolic” devices. We believe this new platform of devices will help to address the recognized limitations of existing obesity therapies (restrictive devices, malabsorption devices, and bariatric surgeries) and will help to transform the way metabolic diseases are treated in the future, starting with Obesity.
Experts' Testimonials
“As a physician who treats obese patients on a daily basis, I am excited to finally have a tool which utilizes the body's natural physiology to achieve appetite suppression. Best of all, this device is minimally invasive, completely reversible, and incisionless.”
— Amol Soin, MD, MBA, MS
Medical Director of Ohio Pain Clinic
“EndoSphere's inventions respond to the urgent need for a less invasive, safer and more physiologic treatment for the growing problem of obesity worldwide.”
— Kenneth Binmoeller, MD
Founder & Chief Medical Officer of Endosphere, Inc.
Founder’s Story
Kenneth Binmoeller, MD
An accomplished innovator and respected leader in the field
Kenneth Binmoeller, MD is among the most published researchers and key opinion leaders in the fields of gastroenterology and endoscopy, having authored more than 300 research papers, articles and books.
An accomplished entrepreneur, Dr. Binmoeller’s first start-up Xlumena was acquired by Boston Scientific for $75 million.
Dr. Binmoeller recognized the huge unmet market need for a new and smarter approach for treating obesity that works with human physiology.
How the EndoSphere System works
Endoscopic insertion of device
The device is inserted to float within the Duodenum because that organ is widely recognized as the body’s Metabolic Control Center.
Recalibration of the Duodenum
At its core, the EndoSphere System amplifies Satiety feedback loops by recalibrating the Duodenum to respond faster and longer to food intake. This accelerates Satiety, thereby reducing appetite and slowing digestion.
Removal of device
EndoSphere’s device is endoscopically removed in a matter of minutes.
The Endosphere System is an endoscopically-inserted device that uses the body’s Natural Physiology to amplify Satiety, rather than antagonizing it.
